Lei, P., Ayton, S., Finkelstein, D., Spoerri, L., Ciccotosto, G., Wright, W., Wong, B., Adlard, P.,  Cherny, R., Lam, L., Roberts, B.R., Volitakis, I., Egan, G., McLean, C., Cappai, R., Duce, J., Bush, A.I. Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export. Nature Medicine (2012) 18: p. 291-295.

McColl, G., Roberts, B.R., Pukala, T., Kenche, V., Roberts, C., Link, C., Ryan, T., Masters, C.L., Barnham, K.J., Bush, A.I., Cherny, R. Improved model of Aß1-42 toxicity in C. elegans shows rapid protection by 8-hydroxyquinoline. Molecular Neurodegeneration (2012) 7(1): p. 57.

Ryan, T., Friedhuber, A., Lind, M., Howlett, G., Masters, C.L., Roberts, B.R. Small Amphipathic Molecules Modulate Secondary Structure and Amyloid Fibril-forming Kinetics of Alzheimer Disease Peptide Aß1-42. Journal of Biological Chemistry (2012), 287: p. 16947-16954.

Hung, L., Villemange,  V., Cheng, L., Sherratt, N., Ayton, S., White, A., Crouch, P., Lim, L., Leong, S., Wilkins, S., George, J., Roberts, B., Pham, C., Chiu, F., Shackleford, D., Powell, A., Masters, C.L., Bush, A.I., O’Keefe, G., Culvenor, J., Cappai, R., Cherny, R., Donnelly, P., Hill, A.,  Finkelstein, D., Barnham. K.J. The hypoxia imaging agent, Cu(ATSM), is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson’s disease. Journal of Experimental Medicine (2012), 209: p. 837-854.

Roberts, B.R., Ryan, T., Bush, A.I., Masters, C.L., Duce, J. The role of metallobiology and amyloid-β peptides in Alzheimer’s disease. Journal of Neurochemistry (2012) 120 S1: p. 149-166.

G. McColl,  S. James, S. Mayo, D. Howard, C. Ryan, R. Kirkham, G. Moorhead, D. Paterson, M. de Jonge, A. Bush. Caenorhabditis elegans maintains highly compartmentalized cellular distribution of metals and steep concentration gradients of manganese. PLOS One (2012), 7: e. 32685 (free access)

D. Hare, M. Gerlach, P. Riederer. Considerations for measuring iron in post-mortem tissue of Parkinson’s disease patients. Journal of Neural Transmission (2012), 119: p. 1515-1521

J. Lear, D. Hare, F. Fryer, P. Adlard, D. Finkelstein, P. Doble. High-resolution elemental bioimaging of Ca, Mn, Fe, Co, Cu and Zn employing LA-ICP-MS and hydrogen reaction gas. Analytical Chemistry (2012), 84: p. 6707-6714

D. Hare, J. Lee, A. Beavis, A. van Gramberg, J. George, P. Adlard, D. Finkelstein, P. Doble. Three-dimensional atlas of iron, copper, and zinc in the mouse cerebrum and brainstem. Analytical Chemistry (2012), 84: p. 3990-3997

D. Hare, C. Austin, P. Doble. Quantification strategies for elemental imaging of biological samples using laser ablation-inductively coupled plasma-mass spectrometry. The Analyst (2012), 137: p. 1527-1537

J. Lear, D. Hare, P. Adlard, D. Finkelstein, P. Doble. Improving acquisition times for elemental bio-imaging using quadrupole-based LA-ICP-MS. Journal of Analytical Atomic Spectroscopy (2012), 27: p. 159-164

SA James, I Volitakis, PA Adlard, JA Duce, CL Masters, RA Cherny & AI Bush. Elevated labile Cu is associated with oxidative pathology in Alzheimer disease, Free Radical Biology and Medicine (2012), 52(2): pp 298-302.

KA Price, JL Hickey, Z Xiao, AG Wedd, SA James, JR Liddell, PJ Crouch, AR White & PS Donnelly. The challenges of using a copper fluorescent sensor (CS1) to track intracellular distributions of copper in neuronal and glial cells, Chemical Science (2012), 3(9): pp 2748-2759

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